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In some embodiments, the otic formulation or composition comprises about 0.02% by weight of the povidone

According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

Serghiou S, Rough K

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Cadenas E., Boveris A., Ragan C.I., Stoppani A.O.M

Long Y, Lin S, Zhu J, Pang X, Fang Z, Lin Y, et al

Understanding epigenetic mechanisms opens new therapeutic possibilities